Frozen Section Biopsy

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An evaluation of frozen section biopsy in 4434 cases.

Frozen section diagnosis is a highly useful method of diagnosis. There were 4434 frozen sections, 24 false positive diagnosis, 65 false negative diagnosis and 30 deferred diagnosis. This method achieves the highest accuracy when there is a cooperation between experienced surgeon and reliable and careful pathologist. It is wise to defer the diagnosis of consult to other pathologist in difficult ...

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Frozen biopsy collection and storage: frozen biopsy samples.

This chapter describes some simple standard operating procedures for the regular collection of samples from surgical resections and their rapid preservation by freezing for long-term cryogenic storage.

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Rapid immunoperoxidase staining of axons for frozen section diagnosis of nerve biopsy specimens.

A new method of freezing and embedding a nerve biopsy specimen and staining it with the immunoperoxidase technique for neurofilaments was developed to overcome the difficulties normally encountered in the assessment of tiny portions of nerve. The method clearly shows the architecture of the nerve, the exact number and size of all axons present, and the degree of fibrosis present. The entire pro...

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CT-assisted stereotactic brain biopsy: value of intraoperative frozen section diagnosis.

In 100 recent CT-guided brain biopsies, the value of intraoperative histologic examination using frozen section technique was evaluated. In 87 of these cases, the biopsy was performed stereotactically. In the remaining 13 cases, a CT-guided free hand technique was used. Of the 100 biopsies performed, adequate tissue for histopathologic diagnosis was obtained in 97, and in three the biopsy was n...

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Frozen section of skin specimens.

CONTEXT Skin cancers are the most common malignancies in this country. Treatment of these tumors often involves assessment of margins, which may be performed by frozen section. OBJECTIVE This article discusses indications for frozen section, various approaches to gross examination of specimens, Mohs micrographic surgery, diagnostic pitfalls, methods to improve diagnostic accuracy, and special...

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ژورنال

عنوان ژورنال: JAMA

سال: 2005

ISSN: 0098-7484

DOI: 10.1001/jama.294.24.3200